The Missouri State Historic Tax Credit provides an incentive for the redevelopment of commercial and residential historic structures. The tax credit is equal to 25% of the eligible costs and expenses of renovation. The tax credit may be used to offset Missouri income tax liability. The credits may be used in the year provided, may be carried back 3 years or carried forward 10 years. Tax credits may be used by individuals, corporations, or partnerships and may also be sold or exchanged. Applications are available by contacting the Missouri Department of Economic Development.

In order to be eligible for the Missouri State Historic Tax Credit, a structure must be listed individually on the National Register of Historic Places, be considered a contributing structure in a National Register historic district, or be located in a local historic district certified by the United States Department of the Interior. Renovation must be equal to or greater than 50% of the total basis of the property (acquisition cost). All plans for renovation must be approved by the Missouri State Historic Preservation Office to ensure compliance with standards for historic preservation.